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Cybernetics And Systems Analysis
International Theoretical Science Journal
UDC 519.217.2
N.Ya. Gridina1, A.M. Gupal2, A.L. Tarasov3, Yu.V. Ushenin4


1 State Institution Romodanov Neurosurgery Institute, National Academy of Medical Sciences of Ukraine, Kyiv

gridinanina@ukr.net

2 V.M. Glushkov Institute of Cybernetics, National Academy
of Sciences of Ukraine, Kyiv, Ukraine

gupalanatol@gmail.com

3 V.M. Glushkov Institute of Cybernetics, National Academy
of Sciences of Ukraine, Kyiv, Ukraine

freearcher@ukr.net

4 V.E. Lashkaryov Institute of Semiconductor Physics, National Academy
of Sciences of Ukraine, Kyiv, Ukraine

ushyury68@gmail.com

ANALYSIS OF NEUROSURGICAL PATHOLOGIES USING BAYESIAN RECOGNITION
PROCEDURES FOR INDICATORS OF SURFACE PLASMON RESONANCE
IN THE AGGREGATION OF BLOOD CELLS

Abstract. The use of the Bayesian recognition procedure for surface plasmon resonance with the addition of verapamil hydrochloride and ketamine to the blood in the analysis of neurosurgical tumor pathologies significantly improved recognition compared to pure blood samples. An analysis of the difference in such pathologies due to the method of surface plasmon resonance with the addition of ketamine made it possible to improve the results of recognition of pathologies as compared with the method of the modified erythrocyte sedimentation rate. It has been possible to achieve a sufficiently high recognition efficiency between tumor pathologies and a healthy state of people.

Keywords: Bayesian recognition procedure, brain gliomas, metastases, traumatic brain injury, surface plasmon resonance, differential diagnosis, modified erythrocyte sedimentation rate.



FULL TEXT

REFERENCES

  1. Matsko D.E., Korshunov A.G. Atlas of tumors of the central nervous system. SPb .: Publishing house of the Russian National Research Chemical Institute named after prof. A.L. Polenova, 1998. 186 p.

  2. Olyushin V.E. Glial brain tumors: a brief review of the literature and the treatment protocol for patients. Neurosurgery. 2005. N 4. P. 41–47.

  3. Zozulya Yu.A., Vasilieva I.G., Glavatsky A.Ya., Rozumenko V.D., Lisyany N.I., Gridina N.Ya. Modern technologies of conservative treatment of gliomas. In: Gliomas of the brain. Ed. Acad. Yu.A. Zozulya. Kiev: UIPK "ExOb", 2007. P. 383–509.

  4. Rozumenko A.V., Kliuchka V.M., Rozumenko V.D., Fedorenko Z.P. Survival rates in patients with the newly diagnosed glioblastoma: Data from the National Cancer Registry of Ukraine, 2008–2016. Ukrainian Neurosurgical Journal. 2018. N 2. P. 33–39. https://doi.org/10.25305/unj.124878.

  5. Dvorak H.F. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 1986. Vol. 315, Iss. 26. P. 1650–1659.

  6. Kudravi S.A., Reed M.J. Aging, cancer, and wound healing. In Vivo. 2000. Vol. 14. P. 83–92.

  7. Vdovin V.A., Muravyov A.V., Pevzner A.A. A method for determining the degree of aggregation of blood cells. Yaroslavl Pedagogical Bulletin. Ser. "Natural Sciences". 2012. N 3. P. 151–154.

  8. Coussens L.M., Werb Z. Inflammation and cancer. Nature. 2002. Vol. 420. P. 860–867.

  9. Colotta F., Allavena P., Sica A., Garlanda C., Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis. 2009. Vol. 30, N 7. P. 1073–1081.

  10. Mantovani A., Allavena P., Sica A., Balkwil F. Cancer-related inflammation. Nature. 2008. Vol. 454. P. 436–444.

  11. Fernandes J.V., Cobucci R.N., Jatoba C.A., Fernandes T.A., de Azevedo J.W., de Araujo J.M. The role of the mediators of inflammation in cancer development. Pathol. Oncol. Res. 2015. Vol. 21, N 3. P. 527–534.

  12. Gridina N.Ya., Shvachko L.P, Draguntsova N.G. Tumor-associated inflammation mechanisms correction by verapamil at brain gliomas progression. Europtan Journal Pharmaceutical and Medical Research (EJPMR). 2016. Vol. 3, N 8. P. 73–78.

  13. Gridina N.Ya., Maslov V.P., Kotovsky V.Y., Draguntsova N.G. Peculiarities of the spectrum of chromosome aberrations in the peripheral blood lymphocytes in cases of brain gliomas and their correction with verapamil and ketamine. Scholar Journal of Applied Medical Sciences (SJAMS). 2015. Sep. 3(6A). P. 2156–2160. URL: http://saspublisher.com/wp-content/uploads/2015/09/SJAMS-36A -2156-2160.pdf.

  14. Davydova O.N., Boldyrev A.A. Glutamate receptors in the cells of the nervous and immune systems. Annals of Clinical and Experimental Neurology. 2007. Vol. 1, N 4. P. 28–34.

  15. Gridina N.Ya., Gupal A.M., Tarasov A.L. Bayesian procedures for the recognition of inflammatory processes in gliomas of the brain. Kibernetika i sistemnyj analiz. 2017. Vol. 53, N 3. P. 41–48.
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